Background: Diabetes mellitus (DM) has become a major public health concern worldwide. The aim of this study was to investigate the factors affecting glycemia in type 2 diabetics in Rajshahi, Bangladesh.

Methods: A cross-sectional study was carried out on a total of 482 T2DM patients in Rajshahi. All available last readings for blood glucose (FBS and 2 h ABF), HbA1c, lipid profile, and other clinical characteristics were obtained from patients’ records. Chi-square test and multivariable binary logistic model were applied in this study.

Results: 64.2% DM patients was observed to have no glycemic control (FBS≥6.1mmol/L, HbA1c≥6.0). Multivariable binary logistic regression model provided the following twelve predictors of glycemic control: (i) knowledge on diabetes (p<0.01), (ii) triglyceride (p<0.01), (iii) low-density lipoprotein (p<0.05), (iv) hypertension (p<0.01), (v) dietary modulation (p<0.01), (vi) anti-diabetic drug (p<0.01), (vii) regular attended health education (p<0.01), (viii) financial support (p<0.05), (ix) family support (p<0.01), (x) regular hospital visit (p<0.01), (xi) diabetic relative (p<0.01) and (xii) patients’ education (p<0.01).

Conclusion: A combined negative effects of several factors on the poor glycemic control was observed in this study. Health education and self-motivation of patient and family awareness are to be intensified by the health authorities of Bangladesh.