Determination of sex from the human remains is very much important and necessary in both living and dead persons for medico-legal and anthropological perspectives. Bones often survive by the long process of decay and provide the major evidence of age and sex of human remains. The mandible is the best material for this study because mandible takes more time to decay. The present study is based on (125) adult dry human mandibles of known sex. Out of (125) dry mandibles (80) were of male and (45) were of female individuals. These mandibles are collected from the Department of Anatomy of Maharishi Markandeshwar Medical College and Hospital, Kumarhatti District Solan, Himachal Pradesh, India. Various measurements are taken from its selected points as described in the paper and recorded in tables. Mean value of measurements of right and left side of male and female mandibles are taken separately. The average value of the width between mandibular foramen to mandibular foramen and the difference between male and female is 3.30 mm which is more in male than in female mandibles. The average width between medial poles of right and left condyles is 2.22 mm more in case of male mandible than in female. The average heights of coronoid process, condyloid process, height of notch of mandibles from base of the mandible, distance between mental foramen and the base of the mandible are 4.86 mm, 3.38 mm, 6.14 mm and 2.03 mm respectively more in males than in females . The average angle of the mandible is 5.280 more in female mandible than male. The mandibular index is 93.27% and 98.09% in male and female respectively. The mandibular index is more in female as compared to male. All these differences in measurements will help in the determination of the sex of the mandible which is a major aim of our study. The present study is compared with standard literature and studies done by other authors. The present study will be helpful for forensic medicine, forensic dentistry, anthropologists and maxillofacial surgeons.