Background: Women have unique health issues and these are paid increased concern in recent time. Pregnancy is an important event for reproductive-age women, where in nine months body undergoes many physiological changes. Even though these changes are normal, women experience a substantial decline in health status during and after pregnancy. Quality of life (QOL) is used to define overall wellbeing of person and it includes physical, psychological, social, economic and political perspectives. In recent times medical decision making research have focused increasingly on health related quality of life (HRQOL) as an important variable as this can benefit patients, clinicians, researchers and health maintenance organizations. Aim: The study was done to determine the impact of parity status among women on their health related quality of life. Method: Total 60 female subjects meeting the inclusion criteria constituted population of the study. The health related quality of life was assessed using SF-36v2 questionnaire. Results: The analysis of coefficient of correlation for SF-36v2 components indicated significant negative correlation between parity status and seven components of SF-36v2: PF (r = -0.49), RP (r = -0.39), BP (r = -0.51), GH (r = -0.42), VT (r = -0.43), RE (r = -0.29) and MH (r = -0.41) at p<=0.05. Whereas, a non-significant correlation was observed between parity and one of the component SF (Social Function) of the questionnaire, SF (r = -0.14) at p<=0.05. Scoring of SF- 36v2 questionnaire also provided total component scores i.e. PCS (Physical Component Score) and MCS (Mental Component Score). Coefficient of correlation analysis for PCS (r = -0.50) and MCS (r = -0.30) showed significant negative correlation with parity status at p<=0.05. Conclusion: Females with higher parity status tend to have poorer health related quality of life.